Colchicine reduces inflammatory to urate crystals, possibly by inhibiting the migration of granulocytes into the inflamed area. It also disrupts cytoskeletal functions by inhibiting β-tubulin polymerisation into microtubules, preventing activation, degranulation, and migration of neutrophils associated w/ mediating some gout symptoms.
GO TO DETAILS ProductsColchicine reduces inflammatory to urate crystals, possibly by inhibiting the migration of granulocytes into the inflamed area. It also disrupts cytoskeletal functions by inhibiting β-tubulin polymerisation into microtubules, preventing activation, degranulation, and migration of neutrophils associated w/ mediating some gout symptoms.
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